AP® Biology Course and Exam Description

AP® Biology builds your college-ready science foundation through labs and real practice. Get ready to score well in your class and on your exam with our guide.
Illustration of a cell from UWorld’s AP Biology Course

AP Biology consists of 2 main sections — Science Practices and Course Content. Course content is divided into units, which are further broken down into topics. Each unit is based on 4 Big Ideas, which are biological concepts you need for a solid foundation in biology. The exam includes 60 multiple-choice questions (MCQs) and 6 free-response questions (FRQs) from these units, each with varying weights.

AP Biology Science Practices

Science Practices are essential skills that foster critical thinking and analysis. There are 6 practices you will master by the end of your AP Biology course.

Science Practice Concept Explanation
Concept Explanation
  • Describe and explain biological concepts and processes, including their application in various contexts
Visual Representations
  • Describe and explain characteristics of visual representations of biological concepts and processes, including their relationships to theoretical and applied contexts
  • Represent and analyze relationships within biological models, such as diagrams, flowcharts, systems, and mathematical models, and relate them to larger biological principles
Questions and Methods
  • Formulate or identify a testable question grounded in an observation, data, or model
  • Define the null hypothesis and predict potential outcomes of an experiment
  • Design experimental procedures that align with the question, ensuring:
    • Proper identification of dependent and independent variables.
    • Selection and justification of appropriate control groups.
  • Suggest a revised investigation based on the assessment of the experimental design or evidence. 
Representing and Describing Data
  • Create visual representations of data, such as graphs, scatter plots, or charts (e.g., bar graphs, histograms, line graphs, pie charts, box-and-whisker plots), ensuring:
    • Selection of the appropriate graph type for the dataset
    • Accurate labeling of axes with appropriate units and legends
    • Proper scaling of axes
    • Precise plotting of data points, including error bars
    • Addition of trend lines to illustrate patterns
  • Interpret data from tables or graphs by:
    • Identifying specific data points
    • Highlighting trends and patterns within the dataset
    • Explaining relationships between variables
Statistical Tests and Data Analysis
  • Conduct mathematical calculations, including:
    • Applying equations outlined in the curriculum
    • Calculating means, rates, ratios, percentages, and percent changes
  • Utilize statistical tools such as confidence intervals and error bars to assess whether sample means differ significantly.
  • Perform chi-square tests to evaluate hypotheses.
  • Analyze data to assess hypotheses or predictions, determining whether to reject or fail to reject the null hypothesis.
Argumentation
  • Make a claim
  • Support claims using evidence
  • Reason
  • Explain relationships
  • Predict causes and effects

AP Biology Course Content

The 8 AP Biology units are based on 4 Big Ideas. We will look at the Big Ideas first, then explain the individual units.

To enhance your understanding of these concepts, explore our AP Biology Study Guide, available in both print and digital formats, featuring 120+ end-of-topic Check for Understanding questions designed to solidify your knowledge.

4 Big Ideas in AP Biology Curriculum

Big Ideas are the themes explored throughout the curriculum. These AP Biology key concepts are interwoven throughout each of the course’s units because they apply in different ways.

Big Ideas

Big Idea 1: Evolution (EVO)
  • The process that drives diversity and unity of life
  • Change of gene frequencies in a population over time leading to biodiversity within and among species
  • Charles Darwin's theory of natural selection explains how populations evolve through accumulating changes in their genes
  • Environmental changes, natural catastrophes, and human-induced events alter gene pools, leading to further evolution

Units: Cell Structure and Function, Heredity, Natural Selection, and Ecology

  • Biological systems depend on energy and molecules to grow, reproduce, and maintain homeostasis
  • Living systems employ various methods to attain, use, and store energy
  • Energy deficiencies can have detrimental effects on populations and ecosystems

Units: Chemistry of Life, Cell Structure and Function, Cellular Energetics, Cell Communication and Cell Cycle, and Ecology

  • Living systems store, retrieve, transmit, and respond to information essential to life processes
  • Genetic information stored in DNA is passed from parent to offspring, influencing survival, growth, and reproduction
  • Non-inheritable information influences behavior between cells, organisms, and populations, crucial for evolution and natural selection

Units: Chemistry of Life, Cell Communication and Cell Cycle, Heredity, Gene Expression and Regulation, and Ecology

  • Biological systems interact with each other exhibiting complex properties
  • Interactions occur at molecular and ecosystem levels, enhancing diversity and resilience to environmental changes

Units: Chemistry of Life, Cell Communication and Cell Cycle, Cellular Energies, Heredity, Natural Selection, and Ecology

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AP Biology Units and Their Topics

The course is divided into 8 units, each focusing on the 4 Big Ideas. Let’s take a look at each unit's weightage and AP Biology topics.

Unit 1: Chemistry of Life

8%-11% Exam Weighting | 5-7 Class Periods)

Unit 1 covers the chemical building blocks of life, focusing on elements for carbon-based systems and topics such as water significance, energy acquisition, and macromolecule exchange.

The Big Ideas explored in this unit: 

  • Big Idea 2: Energetics: The role of energy in the synthesis and breakdown of polymers
  • Big Idea 3: Information Storage & Transmission: The transmission of information between living systems to ensure survival
  • Big Idea 4: Systems Interactions: The importance of water’s polarity in living systems

Unit 2: Cell Structure and Function

(10%-13% Exam Weighting | 11-13 Class Periods)

Unit 2 dives into topics including the cell membrane, homeostasis, organelles, and cellular products and explores the connection between organelles and other cellular components.

The Big Ideas explored in this unit:

  • Big Idea 1: Evolution: The eukaryotic cell’s origin
  • Big Idea 2: Energetics: The advantages and disadvantages of cellular compartmentalization and the role of transport mechanisms involving the cell membrane in the conservation of energy
  • Big Idea 4: Systems Interactions: The effect of the presence or absence of subcellular components on living systems

Unit 3: Cellular Energetics

(12%-16% Exam Weighting | 14-17 Class Periods)

Unit 3 explores how cells capture, store, and use energy through processes such as photosynthesis and cellular respiration.

The Big Ideas explored in this unit:

  • Big Idea 1: Energetics: The accumulation and usage of energy by a living system
  • Big Idea 4: Systems interactions: The usage or conservation of energy in relation to external stimuli

Unit 4: Cell Communication and Cell Cycle

(10%-15% Exam Weighting | 9-11 Class Periods)

Unit 4 covers cell communication, transduction pathways, and energy utilization for growth and replication.

The Big Ideas explored in this unit: 

  • Big Idea 2: Energetics: How cells use energy to communicate with each other
  • Big Idea 3: Information storage and transformation: How the cell cycle helps with the retention of genetic information and why cells communicate with each other

Unit 5: Heredity

(8%-11% Exam Weighting | 9-11 Class Periods)

Unit 5 explores the topic of heredity, specifically focusing on the biological concepts and processes involved.

The Big Ideas explored in this unit:

  • Big Idea 1: Evolution: The influence of genetics on our understanding of evolution
  • Big Idea 3: Information Storage and Transmission: The importance of characteristics suppression from one generation to the next and arguing Mendel’s laws
  • Big Idea 4: Systems Interactions: Influence of the diversity of a species on inheritance

Unit 6: Gene Expression and Regulation

(12%-16% Exam Weighting | 18-21 Class Periods)

Unit 6 explores the role of nucleic acids in gene expression and investigates the structural differences between DNA and RNA.

The Big Idea explored in this unit:

  • Big Idea 3: Information Storage and Transmission: The relationship between gene regulation and the continuity of life and the diversification of genetic information from one generation to the next

Unit 7: Natural Selection

(13%-20% Exam Weighting | 20-23 Class Periods)

Unit 7 delves into the concept of natural selection and its role in driving evolution. The main focus is on how populations adapt to their environments to ensure survival and successful reproduction.

The Big Ideas explored in this unit:

  • Big Idea 1: Evolution: Defend the theory of evolution in scientific terms and discuss the conditions that could possibly make a population less or more likely to evolve
  • Big Idea 4: Systems Interactions: Identify how species interactions can hamper or encourage evolution

Unit 8: Ecology

(10%-15% Exam Weighting | 18-21 Class Periods)

Unit 8 examines ecology, with a focus on the interconnections among biological systems.

The Big Ideas explored in this unit: 

  • Big Idea 1: Evolution: Biodiversity is essential to the survival and evolution of the species within that ecosystem
  • Big Idea 2: Energetics: The relationship between energy and a biological system's health
  • Big Idea 3: Information Storage and Transmission: The effect of disruptions in a biological system on the storage and transmission of genetic information 
  • Big Idea 4: Systems Interactions: The effect of interactions among species on the survival of an ecosystem

Each of these AP Biology units and topics will help you establish a solid and comprehensive understanding of the subject, preparing you for success on the AP Bio exam. Get a sense of how you might be tested on these with our AP Biology practice tests. You can customize each test by selecting the units you want questions from and choose the number of questions you’d like. You’ll get detailed and illustrated answer explanations for each question, plus the ability to create flashcards using spaced repetition.

AP Biology Labs: An Outline

Lab experiments are part of the AP Biology Course and Exam Description (CED). Labs allow you to create scientific questions, perform experiments, and delve into course subjects. Thirteen labs covering ideas such as artificial selection, diffusion, osmosis, and cellular processes improve your scientific reasoning and analysis skills. They also will help you:

  • Master the subject matter
  • Understand the empirical work
  • Develop practical skills
  • Learn the nature of science
  • Drive your interest in scientific learning
  • Develop your teamwork skills

As part of your labs, you will need to ask questions, design experiments to test your hypotheses, conduct experiments, analyze your findings, and reach conclusive results. To enhance your understanding and prepare effectively, explore our AP Biology online prep course, which offers detailed explanations and practice tools tailored to AP Biology topics.

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Frequently Asked Questions (FAQs)

Here is a list of the most important AP Biology topics based on their exam weighting: 

  • Unit 7: Natural Selection (13%-20%)
  • Unit 3: Cellular Energetics (12%-16%)
  • Unit 6: Gene Expression and Regulation (12%-16%)
  • Unit 4: Cell Communication and Cell Cycle (10%-15%)
  • Unit 8: Ecology (10%-15%) 
  • Unit 2: Cell Structure and Function (10%-13%)
  • Unit 1: Chemistry of Life (8%-11%)
  • Unit 5: Heredity (8%-11%)

No. Taking high school biology is a prerequisite for taking AP Biology.

AP Biology could be considered one of the easier AP science courses. However, it depends on your aptitude for studying biology, the amount of time you can dedicate to studying, etc.

References

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